Publication Bias in Animal Models of Stroke

Sena et al use data contained in the CAMARADES website to show a substantial publication bias exists in animal models of stroke, leading to an absolute overstatement of efficacy of 8%

Dopamine Agonists in Parkinson's Disease

Evelien Rooke and Hanna Vesterinen tackle the animal modelling of Parkinson's Disease, and find low levels of reporting of measures to avoid bias

Animal Models of Intracranial Haemorrhage

Joseph Frantzias and Rustam al-Shahi Salman report a systematic review and meta-analysis of interventions tested in animal models of Intracerebral Hemorrhage

Can Animal Models of Disease Reliably Inform Human Studies?

van der Worp and colleagues explore some of the reasons for translational failure, and discuss measures which might start to put things right

Improving the Translational Hit of MS Research

Hanna Vesterinen's paper shows that problems of internal and external validity are also common in the experimental allergic encephalomyelitis literature