CAMARADES Centres
University of Edinburgh:
- Malcolm Macleod
- Emily Sena
- Hanna Vesterinen
- Kieren Egan
- Lizzy Cottrell
- Peter Sandercock
National Stroke Research Institute, Melbourne, Australia
- David Howells
- Tori O’Collins
- Ana Antonic
- Geoff Donnan
University of Nottingham
- Philip Bath
University Medical Centre Utrecht, Netherlands
- Bart van der Worp
Charite, Berlin, Germany
- Ulrich Dirnagl
- Nicolas Crossley
University of Adelaide, South Australia
- Simon Koblar
IBMC, Porto, Portugal
- Orsolya Varga
- Anna Olsson
Val d'Hebron, Barcelona
- Dolors Casellas
- Joan Montaner
Funding:
The Edinburgh group acknowledge the support of the MRC Trials Methodology Hub, the MS Society, and the Scottish Chief Scientist Office
Sena et al use data contained in the CAMARADES website to show a substantial publication bias exists in animal models of stroke, leading to an absolute overstatement of efficacy of 8%
Evelien Rooke and Hanna Vesterinen tackle the animal modelling of Parkinson's Disease, and find low levels of reporting of measures to avoid bias
Joseph Frantzias and Rustam al-Shahi Salman report a systematic review and meta-analysis of interventions tested in animal models of Intracerebral Hemorrhage
van der Worp and colleagues explore some of the reasons for translational failure, and discuss measures which might start to put things right
Hanna Vesterinen's paper shows that problems of internal and external validity are also common in the experimental allergic encephalomyelitis literature